LUYOR-3480微孔板細胞輻照儀是用于體外光遺傳(In Vitro Optogenetics)研究的一款LED輻照光源,是一款體外細胞培養(yǎng)光遺傳刺激系統(tǒng)。體內光遺傳學已成為研究小鼠、大鼠和其他動物神經回路的標準技術。但隨著光激活蛋白和其他光反應工具數量的增加,該技術現在經常用于多孔板和細胞培養(yǎng)皿中,用于組織培養(yǎng)、細菌、斑馬魚、幼蟲和其他研究模型的研究。LUYOR-3480微孔板細胞輻照儀可以提供理想的輻照波長和光強度、輻照時間可以控制,輻照儀的光源能夠放置到細胞培養(yǎng)箱長時間工作。
上圖:LUYOR-3480-470nm
LUYOR-3480微孔板細胞輻照儀的特點:
1.輻照光源特別適用于96孔板,滿足 6、12、24、48 和 96 孔板。
2.光源部分和控制器連接線長2米,輻照儀光源部分能夠放置在細胞培養(yǎng)箱里面長時間工作。
3.光源部分能夠滿足培養(yǎng)箱的高濕度環(huán)境工作。
4.輻照光強度可調。
5.輻照時間可調。
6.可選波長:365nm、405nm、420nm、450nm、470nm、525nm、590nm、630nm、660nm、740nm、808nm等
LUYOR-3480微孔板細胞輻照儀用于:
1.干細胞 (iPSC) 分化Stem cell (iPSC) differentiation
2.發(fā)育生物學 Developmental biology
3.分子生物學Molecular biology
–受體定向蛋白表達(通過 Cry2 激活)receptor directed protein expression (via Cry2 activation)
4.CRISPR/Cas9基因修飾CRISPR/Cas9 gene modification
5.腫瘤學 Oncology
6.眼科和眼科藥物開發(fā)Ophthalmology & ophthalmologic drug development
7.光刺激和蛋白質漂白Photostimulation and bleaching of proteins
8.通道病,例如癲癇和心律失常。Channelopathies such as epilepsy, and arrhythmias.
9.光藥理學Photopharmacology
10.光解籠Photo-uncaging
11.光開關激酶抑制劑的創(chuàng)建Photoswitching
12.光動力療法的發(fā)展Development of Photodynamic therapies
13.光化學Photochemistry
LUYOR-3480 Well Plate Illuminator
LUYOR-3480 Well Plate Illuminators are benchtop reactors designed for use in the research or education lab. The LUYOR-3480 is designed for use with a 24 Well Plates or with vials. Currently offered in 400 nm, Cool White 4000K, Blue, Green, broad Green (Lime GR2), Amber, Red and 720 nm (Deep Red).
LED Arrays for optogenetics and photochemistry in well plates
Optogenetics
In-vivo optogenetics has become a standard technique for studying neural circuits in behaving mice, rats, and other animals. But as the number of light-activated proteins and other photoreactive tools has increased, this technology is now used frequently in multi-well plates and cell culture dishes for studies in tissue culture, bacteria, zebrafish, larvae, and other research models.
For these purposes, illumination systems need to be programmable to deliver pulses of light with the correct intensity, timing, and duration. They also need to be incubator compatible. Our LUYOR-3480 series of well plate illuminators were designed to fill this role.